Transbronchial Lung Biopsy

نویسندگان

  • Prasoon Jain
  • Sarah Hadique
  • Atul C. Mehta
چکیده

Transbronchial Lung biopsy (TBBx) also known as “Bronchoscopic Lung Biopsy” is one of the most important sampling procedures performed during fl exible bronchoscopy. In majority of cases, TBBx is performed under conscious sedation in an outpatient setting. TBBx is performed for obtaining tissue specimen from peripheral lung masses and focal or diffuse lung in fi ltrates. The technique is useful in patients with suspected lung cancer, fungal and mycobacterial lung infections, unexplained in fi ltrates in immunocompromised hosts and in patients with suspected pulmonary sarcoidosis, lymphangitic carcinomatosis, and in selected cases of pulmonary Langerhan’s cell histiocytosis, lymphangioleiomyomatosis, and cryptogenic organizing pneumonia. TBBx also plays important role in assessment of rejection and infectious complications following lung transplantation. TBBx is not useful for histological diagnosis of idiopathic pulmonary fi brosis or for distinguishing histological subtypes of idiopathic interstitial pneumonia. The diagnostic yield is also suboptimal in lung nodules smaller than 2 cm in diameter. Several recent techniques such as radial probe endobronchial ultrasound with guide sheath, electromagnetic navigation bronchoscopy, and virtual bronchoscopy navigation have been devised to improve the diagnostic yield of TBBx for solitary lung nodule. Hemoptysis and pneumothorax are the two leading complications of TBBx, occurring in less than 2 % of cases. Every bronchoscopists must be able to perform TBBx. Transbronchial Lung Biopsy Prasoon Jain, Sarah Hadique, and Atul C. Mehta

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تاریخ انتشار 2017